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6,7,8 With the rapid development of geriatric medicine and aging biology, increasing evidence reveals the close link between the aging progression/senescence development and the dysregulated cellular metabolism, especially the dysregulated metabolism of glucose and lipids

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Experimental Section Materials 1-Methylnicotinamide chloride, glutathione, and all other chemicals were purchased from Sigma-Aldrich (Saint Louis, MO, USA) and used without further purification