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Boca Raton, FL, USA: 1996
336 For example, in mice with myocardial ischemia-reperfusion, Drp1-mediated mitochondrial fission is upregulated, while Drp1 inhibitor can down-regulate mitochondrial fission, increase ATP, and improve cardiac function
The blockade of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) mRNA by the use of siRNA promotes a reduction of INF- in lymphocytes [136]
These effects were linked to the inhibition of the NF-B signaling pathway, further underscoring the anti-inflammatory activity of ALA [43]
