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The FDA cited three concerns: potential immunogenicity (the peptide could trigger immune reactions), manufacturing impurity risks (synthetic peptides can contain truncated sequences and other contaminants), and a lack of human safety data sufficient to evaluate risk

This fragment was first isolated and studied in the 1980s and 1990s by researchers investigating which portions of the growth hormone molecule were associated with different structural domains

Suspected adverse drug reactions can also be reported via the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk)

GR is a flavo-protein oxidoreductase ubiquitously present in both prokaryotes and eukaryotes (Romeo-Puertas et al., 2006)