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Once inside the enterocytes, heme oxygenase-1 (HO-1) extracts ferrous iron from the heme, releasing it into the cytoplasm (Figure 1)
For many, these signs might lead them to wonder about their vitamin B12 levels
The two-electron oxidation of a thiol(ate) residue by reactive oxygen or nitrogen species, such as H 2 O 2 or peroxynitrite, yields a cysteine-sulfenic acid (SOH) intermediate that is highly reactive and metastable [15,75]
