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Aloe Vera Leaf Gel Extract A demulcent that has been used throughout history, aloe vera has long been known to maintain normal inflammatory balance

Furthermore, their quinidinelike effect on cardiac conduction, which can prolong the QTc interval, necessitates careful cardiovascular screening and often precludes their use in elderly patients or those with preexisting heart disease, frequently positioning them as a secondary choice after SNRIs or gabapentinoids [45, 336, 368, 369]

Nevertheless, increasing evidence suggests that phytomolecules can modulate brain insulin resistance and enhance incretin signaling, which contribute to their neuroprotective effects in PD

P21: Like PE-22-28, human dosing protocols are not established through clinical trials