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Drug approval for the treatment of geographic atrophy: How we got here and where we need to go
This patient's normal height and weight percentiles suggest early disease before significant bone age advancement
found that the abnormal accumulation of double-stranded DNA in the cytoplasm may bind to the cytoplasmic DNA sensor (cGAS), thereby specifically triggering the STING-interferon (IFN) signaling pathway in microglia, promoting the expression and secretion of inflammatory cytokines
Shieh SY, Ikeda M, Taya Y and Prives C
