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Description
cruzi infection induces multiple alterations in the thymic microenvironment, impairing normal T cell development and likely driving the abnormal, premature export of immature double-negative and double-positive thymocytes with a pro-inflammatory activation profile to the periphery (Prez et al., 2020)
Moreover, HO-1 promotes heme breakdown, which increases intracellular free iron levels and expedites the ferroptotic process (Chiang et al., 2018)
[DOI] [PubMed] [Google Scholar] 343.Eid HM, Lyberg T, Larsen J, Arnesen H, Seljeflot I
May 2012;126(5):464-9
