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This method has its pros and cons, while being helpful to measure cytokines potentially at a more localized level, these PBMCs can be affected by cryopreservation, length of storage, and the overall processing methods
However, several studies in plasma patients seem to agree on the increase in oxidative stress and on the decline of GSH and GSH-related enzymes [279]
Conditions like uncontrolled diabetes or intracranial hypertension, for example, might also warrant caution or closer monitoring if sermorelin is used
