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Kidneys: The kidneys contain significant amounts of vitamin B12
Brumatti LV, Marcuzzi A, Tricarico PM, et al
This has noticeably been the case for synthetic oleanane triterpenoids that enhance NRF2 activity: these agents can be antioxidative and cytoprotective at low doses, but be pro-oxidative and cause DNA damage and apoptosis at higher doses (59,60)
these changes showed up by week 3 and held at 2 months
