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Sym004 also demonstrated efficacy in cetuximab-resistant CRC xenograft models harboring mutations in EGFR, S492R EGFR-mutant DCR7, and G465R EGFR-mutant LIM1215 (Sanchez-Martin et al., 2016)
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[PUBMED Abstract] Zuna J, Hovorkova L, Krotka J, et al.: Minimal residual disease in BCR::ABL1-positive acute lymphoblastic leukemia: different significance in typical ALL and in CML-like disease
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