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as a result, surfactant production decreases markedly, which in turn causes alveolar fluid accumulation leading to alveolar collapse and ARDS (Matthay and Zemans, 2011

It is rational to suppose that the BAT5, which imports the 2-keto-acid MTOB into the chloroplasts, also exports the chain-elongated 2-keto-acids back into the cytoplasm

it modulates pathways that contribute to cellular homeostasis, neuronal metabolism, and tissue regeneration, thereby maintaining reduced oxidative stress and promoting neuronal health AD, PD, HD, MS, and ALS, reviewed in Ref