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In this study, we investigated how infection with the Lyme disease-causing bacterium Borrelia burgdorferi ( Bb ) affects host metabolic pathways and how these metabolic pathways may impact host defense

481 However, the hydrophilic structure of deferoxamine results in poor absorption and rapid metabolism which forces frequent parenteral administration in patients (over 8 to 12 h per day), thus imposing a significant treatment burden

134 Furthermore, the expression of enzymes associated with histone ubiquitination is also dysregulated in tumors