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Description
CRP is a key indicator of the inflammatory process
Under unfolded protein stress conditions, GRP78 binds to unfolded or misfolded proteins and subsequently activates downstream ER stress sensors, including IRE1, PERK, and ATF6, to trigger a response to unfolded proteins (Yoboue et al., 2017) , (Wei et al., 2012)
Similarly, the tumor suppressor protein p53, known for its multifaceted roles in maintaining genomic stability and orchestrating cellular stress responses, exerts intricate control over glutamine metabolism [32]
2 Behl PN, Bhatia RK
