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The strongest published finding is from the foundational Biochemical Pharmacology study by Neelakantan et al.: in diet-induced obese mice, daily 5-Amino-1MQ administration produced reductions in body weight, white adipose tissue mass, and adipocyte size without any significant change in food intake

AOD-9604 targets fat cells primarily through beta-3 adrenergic receptors, which are G-protein coupled receptors predominantly expressed in adipose tissue

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