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Description
Pre-Treatment Considerations
Treatment with Stattic led to a decrease in JAK2/STAT3 pathway activation (phosphorylation), which mitigated the EMT progression (Figure 3G)
Airway hydration and COPD
Prior to in vivo PK dosing, in vitro experiments may be performed to predict metabolic stability, cell permeability potential, protein binding, and drug-drug interaction potentials
