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Nature Structural & Molecular Biology

doi: 10.1074/jbc.M114.600320 50 ChenT.KogaK.DescalziG.QiuS.WangJ.ZhangL

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Administration of vupanorsen led to significant reductions (approximate values) in TGs (2444%), remnant cholesterol (2438%), non-HDL-C (1019%), apo-B (39%) and apo-CIII (3658%)