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These autoantibodies against immunomodulatory proteins (including cytokines, chemokines, complement components and cell-surface proteins) could attack tissues of patients, thereby impair host cell signals, perturb immune function, damage organ systems, and increase COVID-19 severity 36

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Third, increasing levels of ROS have been linked to lower sperm counts.[ , ] Fourth, any change in gonadotropin levels may have an impact on spermatogenesis.[] Our results indicated that CYP exposure could cause a reduction in FSH and LH levels that might be accountable for the sperm impairment observed in this study

Amsterdam: Elsevier Inc