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Fe 3+ absorbed into the cell is located in the endosomes and is reduced to ferrous iron (Fe 2+ ) by transmembrane epidermal antigen of prostate 3 (STEAP3) [70]

Functional enrichment showed that this pattern primarily involved Plant-pathogen interaction, Protein processing in the endoplasmic reticulum, Carbon metabolism, and Glutathione metabolism ( Figure 4B )

t = 0.352

Despite little evidence of effectiveness through oral supplementation, the few in vitro studies of direct vitamin C treatment onto airway cells show possible antioxidant and antiviral properties