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10.7554/eLife.73456 147 ScheltensP.De StrooperB.KivipeltoM.HolstegeH.ChtelatG.TeunissenC
doi: 10.1111/j.1471-4159.2012.07734.x
In addition, the Rumack nomogram was initially designed and intended for use within the first 24 h of the APAP overdose and is based on anticipated drug clearance following a single, acute ingestion of a toxic dose of APAP (Rumack 2002)
Wrinkle depth may reduce measurably during this phase
