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Critically short telomeres signal the cell to enter senescence or apoptosis, contributing to tissue aging and dysfunction

Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F

Short-term IP dosing elicited stronger transcriptional activation in females despite behavioral improvement being restricted to males, whereas longer-term IN treatment improved performance in both sexes despite divergent molecular responses

Previous studies have highlighted the important role played by hepatocyte gap junctions (GJs) with regard to increasing the severity of APAP-induced liver toxicity
