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There was also a considerable drop in the size of the kidneys from 5.5 to 2.8% as well as the reciprocal slope of the serum creatinine level from 3.81 to 2.61 mg per mL-1/year (240, 254)

Its primary mechanism of action is the activation of telomerase, an enzyme critical for maintaining telomere length and cellular replicative capacity, which has positioned it as a key compound in gerontology and aging research [3]

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The first-line treatment is rigorous daily sun protection and the association of tinted sunscreen with topical bleaching agents, which may have a different action on melanogenesis
