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Multiple phosphorylation sites have been identified on both ER and ER 81,82 , supporting this hypothesis, though these sites have yet to be reported in zebrafish
This is the same pathway that microneedling and laser resurfacing stimulate mechanically
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Neuroinflammation and Brain Injury: It reduces neuroinflammation and supports nerve regeneration, potentially aiding recovery from traumatic brain injuries and protecting against neurodegeneration in conditions like Parkinsons or Alzheimers (though evidence is preliminary)
