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In the brain, L-carnitine challenge was accompanied by an increase in total acylcarnitines in both E3 and E4 mice but not in E2 mice (Figure 9B)

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China Tropical Med 2007;7(5):753-754

TMAO t 1/2 was estimated by fitting linear regression to log-transformed concentrations over the final three time points of each curve, corresponding to the terminal elimination phase, following standard log-linear pharmacokinetic modeling methods