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In a mouse model of neuroinflammation, these extracellular vesicles can help neurons take in more mRNA ( 3.5 Focused ultrasound (FUS) FUS represents a non-invasive physical regulation method that provides an innovative approach for the reversible opening of the BBB and brain drug delivery through the synergistic effect with intravenous MBs (Rezai Ali et al., 2024

For example, anaemia of chronic disease will produce a raised ferritin result, but iron deficiency anaemia will produce a low ferritin result

We have found that many of these effects appear to be mediated by the ability of CCN proteins to engage integrins

Cold-chain integrity from origin to delivery