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While numerous synbiotic formulations have demonstrated potential in modulating gut microbiota and reducing uremic toxin levels in patients with CKD, their translation into routine clinical practice remains limited

Further molecular study in the presence of BsGGT large subunit showed that the induction of osteoclastogenesis was related to upregulation of an osteoclast differentiation factor receptor activator of nuclear factor kappa-B ligand (RANKL), which interacted with surface receptors of precursor osteoblast cells and promoted the formation of osteoclast cells

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4, 124133 10.1038/ncb744 [DOI] [PubMed] [Google Scholar] 110.Yoshino, A., Setty, S.R.G., Poynton, C., Whiteman, E.L., Saint-Pol, A., Burd, C.G.et al