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In addition, RRM2 may exert its regulatory role by activating EGFR/AKT

The increase in Grx3 expression was associated with several solid tumours, including an increase in proliferation in colon and lung cancer [197], migration and invasion in oral squamous cell carcinoma [198], and growth and metastasis in nasopharyngeal carcinoma [199]

[] These findings suggest that ICIs may be a promising treatment option for NF1-mutated cancers, warranting further investigation in clinical trials

Some patients may experience a mild sensation at the injection site, but there is little to no downtime, allowing you to resume normal activities immediately