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Current senolytic agents are primarily employed in cancer therapies, such as doxorubicin, trametinib, and cell cycle-targeting drugs like palbociclib (Lea et al., 2022
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Cotreatment with gedunin and epalrestat induced G1/S phase cell cycle arrest, and cell death initially by autophagy and subsequently by apoptosis
Fratta Pasini AM, Stranieri C, Ferrari M et al (2020) Oxidative stress and Nrf2 expression in peripheral blood mononuclear cells derived from COPD patients: an observational longitudinal study
