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Moreover, inhibition of heat shock factor-1 (HSF-1) dependent heat shock protein beta 1 (HSPB1) expression can also inhibit erastin-induced ferroptosis ( Other than the screened compounds, research has also focused on designing synthetic ferroptosis inhibitors in order to provide potential health benefits to prevent and/or ease the symptom of diseases that are related to ferroptosis

10.3390/ijms23073591 133 PizziC.ManzoliL.ManciniS.BedettiG.FontanaF.CostaG

Lapatinib is an anticancer medication with low molecular weight and lipophilic characteristics that allow it to pass through the bloodbrain barrier (BBB) [9,10]

[DOI] [PMC free article] [PubMed] [Google Scholar] [203].Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J