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Description
B12 is a vitamin that plays a crucial role in cognitive and nervous system functions
The interactions between NNMT and three methionine cycle-related proteins AHCY, BHMT, and MAT1A were validated through Co-IP followed by immunoblotting in mouse liver and 293 T cells [40]
Knockdown of NNMT in adipocytes was associated with increased NAD+ levels and altered expression of genes involved in energy expenditure, providing the rationale for pharmacological NNMT inhibition [2]
doi:10.3390/jcm13082176
