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The downregulation of exosome-derived miR-149-3p contributed to T-helper type 17 (Th17) cell differentiation, promoting intestinal inflammation ( Gut Microbiome-Mediated Fibril Formation In PD, -synuclein inclusion bodies evidenced in the brainstem, locus coeruleus, and dorsal motor nucleus of the vagus (DMV), were also present in the stomach, duodenum, colon (Shannon et al., 2012

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It is assumed that the site-specific interaction of the AEDG peptide with DNA leads to a change in the nature of gene expression
