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This situation would lead to a self-perpetuating cycle, in which the free radicals generated would induce GSH depletion, thus increasing oxidative stress that would reduce antioxidant enzyme levels, which would further reduce GSH synthesis

doi: 10.1016/j.fertnstert.2008.02.093 158 YoungVJAhmadSFDuncanWCHorneAW

Transplantation of these Nurr1-modified MSCs into the 6-OHDA model of PD resulted in decrease inflammation, increase dopaminergic neurons, and demonstrated therapeutic potential in the treatment of PD [90]
Identification of QTLs underlying folate content in milled rice
