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Genome-wide association studies (GWAS) have further identified more than 200 genetic loci associated with MS susceptibility, including several genes involved in mitochondrial function and OS defense (UCP3, GRPEL1, TXNRD2, ISCU, AASS, ACADL, DMGDH, and CADS) (International Multiple Sclerosis Genetics C, 2019

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[Google Scholar] 311.Adamo G., Grimaldi N., Campora S., Sabatino M.A., Dispenza C., Ghersi G

Therefore, more research should explore the role TIMP-2 and MMP-2 may have in PTSD, and how they not only relate to central oxidative stress processes, but common somatic comorbidities in PTSD as well