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Individualized titration is essential to achieve serum trough levels in the mid-normal physiologic range, thereby minimizing adverse effects such as erythrocytosis, gynecomastia due to aromatization, or suppression of endogenous spermatogenesis

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Bisubstrate strategies to target methyltransferases

Allicin, a substance abundant in garlic, when consumed in large doses, can be hazardous to the liver (139)
