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Results Monocyte-derived macrophages from Crohns disease display increased sensitivity to H 2 O 2 induced ferroptosis When retrieving macrophages from plastic culture dishes through trypsinization we see a decreased recovery of macrophages from patients with active CD compared to healthy controls (Table 1)

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Phylum porifera encode PRXs sensitive to hyperoxidation, but lack SRX For each of the 19 metazoan species, including phylum Porifera, we identified at least one AhpC-PRX1 sequence encoding the full motifs (GGLG and YF) that confer sensitivity to hyperoxidation (SO 2 H) under high concentrations of H 2 O 2 (Fig

These enzymes efficiently convert various nitriles, including 4-cyanopyridine, iminodiacetonitrile, and mandelonitrile, with high yields and with rapid reaction times