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Coming back to metabolic dysfunctions in opioid addicts, not always overlapping, as evident in Table 3, a systematic review comprehending 46 articles and 37,407 participants suggested that opioids increase serum triglycerides (thus, inducing or worsening hepatic steatosis) and may reduce blood glucose and low-density lipoproteins (LDLs)

Clarke G, Sandhu KV, Griffin BT, Dinan TG, Cryan JF, Hyland NP (2019) Gut reactions: breaking down xenobiotic-microbiome interactions

6) What are the downstream signals associated with ferroptosis

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