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Some interactions may diminish its effectiveness or cause unwanted side effects
One day is better than four days of ejaculatory abstinence for sperm function

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Kciuk M, Kruczkowska W, Gaziewska J, Wanke K, Kauziska-Koat , Aleksandrowicz M, Kontek R (2024) Alzheimers disease as type 3 diabetes: understanding the link and implications
