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Also known as myalgic encephalomyelitis (ME or ME/CFS) or systemic exertional intolerance disease (SEID), this complex disorder causes extreme fatigue

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Recent studies further demonstrate that vascular regression and impaired angiogenesis within the corpus luteum are strongly associated with hypoxia-driven ROS accumulation and subsequent luteal insufficiency [44]

Overall, there is substantial evidence establishing a connection between mitochondrial dysfunction and nuclear DNA damage
