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Notably, the clinical translation of MT remains faced with challenges, including the isolation of mitochondria, transplant rejection, bloodbrain barrier, and ethical issues [367369]

The method optimization takes into account the functional data of GP complex: 1) the peroxilipid is reduced by GSH (reduced glutathione) to hydroxilipids (GP activity)
Superoxide dismutase (SOD) protects cells by converting harmful superoxide radicals into hydrogen peroxide and oxygen, serving as the body's primary defense against oxidative cellular damage
