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The CEDIM trial was a randomized, double-blind, placebo-controlled, multicenter trial in which 472 patients with acute myocardial infarction and high-quality two-dimensional echocardiograms received either placebo (239 patients) or L-carnitine (233 patients) within 24 hours of chest pain onset

International journal for vitamin and nutrition research , 75 (1), 3-9

Mitochondrial dysfunction leads to a loss of energy production, fatty acid accumula- tion, excess reactive oxygen species(ROS) generation, membrane instability, and a shift to glucose metabolism [1,2]