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Among these regulatory systems, three have emerged as particularly compelling therapeutic targets due to their pivotal involvement in both physiological and pathological contexts: The excitatory amino acid transporter 2 (EAAT2, also known as GLT-1 in rodents), aquaporin-4 (AQP4), and purinergic receptors, particularly the P2X 7 and P2Y 1 subtypes

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Featured in a smaller, fragmentary form for easier GI tract absorption, it imparts further anti-inflammatory and immunomodulating benefits for a synergistic healing effect [10, 27, 28, 29]