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Sentrix ID and position-related batch effects were identified by regressing the first three principal components with possible batch covariates

doi: 10.1006/cimm.1995.1144

Studies show that the XPC variants are associated with increased DNA adduct levels after aflatoxin B1 exposure, increasing liver cancer risk.[ref][ref][ref] This means that for people who both accumulate more DNA damage from mycotoxins (because of detox variants) and repair it less efficiently (because of XPC variants), the longterm cancer risk from chronic exposure is significantly higher