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In addition, riboflavin and pyridoxine, which requires riboflavin for its activation, have been shown to have intrinsic neuroprotective properties against glutamate excitotoxicity

While the alkyl chain of the 25 R1 group is elongated by two more methylene groups in 27 , the tertiary amine of 14 was replaced by pyridine to generate 29 and 30 , as pyridine is also nitrogen-containing but neutral at physiological pH (pKa = 5.2)

This review will focus on cardiometabolic, neurological, and musculoskeletal disorders in addition to providing a summary of the most recent literature on the effect of glucosinolates in certain cancers
