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Additionally, studies involving co-administration with insulin in animal subjects have observed increased weight gain and adipose tissue accumulation, suggesting an influence on metabolic regulation

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While Th17 cells can respond appropriately to bacterial and fungal antigens such as Staphylococcus aureus and Candida albicans , their immune responses are not specific to viral antigens [57]

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As such, complex I inhibitors like 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) or rotenone show preferential cytotoxicity to the DA neurons (Blesa and Przedborski, 2014)

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