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Pesticides and other agricultural or industrial chemicals further exacerbate oxidative stress by disrupting redox-sensitive signaling pathways and impairing antioxidant defense mechanisms

The intervention with DSF improved glucose tolerance and insulin sensitivity, while preventing fibrosis and steatosis of the liver and hypertrophy of pancreatic islet cells

Cofactors (e.g., activators and repressors) are key molecules in the determination of downstream responses produced by receptor activation

This imbalance leads to predominant osteoclastic resorption over osteoblastic formation, resulting in progressive bone mass depletion and eventual osteoporotic deterioration (7)