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Furthermore, FGF21, another hepatokine modulated by exercise, has been shown to increase hippocampal synaptic plasticity, reduce systemic inflammation and neuronal cell death, and enhance cognitive function [131]

And how can biology thread the needle between reaching for cellular immortality, and the potential malignant consequences

In the metabolism of aromatic amines, N-hydroxy aromatic amine metabolites generated in the liver enter the bladder via urine and are further acetylated by NAT1 in the bladder epithelial cells, resulting in the production of highly reactive intermediates
