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Neither has been tested in humans, and both carry significant unknowns -- Dihexa with its retracted publication and oncological pathway concerns, PE-22-28 with its untested cognitive effects and potential seizure susceptibility

Vascular injury and thrombotic disorders show interesting preclinical findings with BPC-157 preventing pathological thrombus formation while maintaining physiological hemostasis

The diagnostic pathway typically begins when a patient presents with suggestive symptoms or when deficiency is identified incidentally during routine blood testing
