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Despite unaltered Cldn7 mRNA expression, MMP-7 KO animals displayed significantly higher levels of claudin-7, confirming that MMP-7 fragments Claudin-7 post-translationally [102]

Once natural production resumes, HCG is discontinued to avoid potential desensitization issues

Water-soluble NAs, such as NDMA, NDELA, and NFA were directly dissolved in the respective cell culture medium, whereas water-insoluble NAs were dissolved in DMSO or ethanol (NND, due to low solubility in DMSO)

They are not intended to represent clinical evidence in humans, and Dihexa has not been approved by the FDA, EMA, or any other regulatory authority for any indication