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Description
It is a well-characterized, mechanistically specific peptide with a 30-year research history, a strong clinical safety record from formal trials, and modest but real efficacy data from 12-week studies

In experimental studies, formation of complexes of cellular antigen with antibody resulted in activation of dendritic cells, facilitation of cross-presentation of antigens to tumor-specific CD 8 + T cells and inhibition of tumor growth Fc receptor-targeted antigen uptake was shown to initiate cross-presentation pathways as an immune regulatory mechanism for effective tumor immunity

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doi: 10.1016/j.ocarto.2024.100533 103 JainAGyoriBMHakimSJainASunLPetrovaVet al
