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Unlike in healthy individuals, in individuals with chronic HIV infection, immunosenescence may occur prematurely, primarily because of persistent immune activation, increased cellular replication and apoptosis linked to antiviral responses, and a heightened risk of age-related comorbidities

doi: 10.1016/j.neulet.2005.04.022

PCs are, however, also important for long-distance transport of metals, it remains to be shown, whether the same or other ABC transporter participate in such transport

doi: 10.1093/oxfimm/iqaa005 233 RuanQ.YangK.WangW.JiangL.SongJ