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184,185,203 It is important to note that because most PK-deficient patients are compound heterozygous for two different (missense) mutations, up to seven different tetrameric forms of PK may be present in such patients, each with distinct structural and kinetic properties

Eriksen, S.H., Jensen, B., Schneider, I., Kaasgaard, S

Its high rate of recurrence and the degree of difficulty in achieving a complete cure result in a reduced survival rate for patients
Liver dysfunction in idiopathic pulmonary arterial hypertension: prevalence, characteristics and prognostic significance, a retrospective cohort study in China
